
Getting to the Mayo Clinic from Rochester International Airport (RST) is a straightforward process, offering several convenient transportation options. Located just 8 miles southwest of the airport, the Mayo Clinic is easily accessible by taxi, ride-sharing services like Uber or Lyft, or rental car, with the drive typically taking around 15 minutes. Additionally, the Rochester Public Transit system provides bus service, though it may require a transfer and take slightly longer. For those preferring a hassle-free experience, the Mayo Clinic also offers a complimentary shuttle service for patients and visitors, which can be arranged in advance. Each option ensures a smooth and efficient journey to one of the world’s leading healthcare facilities.
| Characteristics | Values |
|---|---|
| Distance | Approximately 8 miles (13 kilometers) |
| Travel Time | 15-20 minutes by car (depending on traffic) |
| Transportation Options | Car (rental, taxi, rideshare), Shuttle Service, Public Transit (bus) |
| Rental Car Companies | Available at Rochester International Airport (e.g., Enterprise, Hertz) |
| Taxi/Rideshare | Uber, Lyft, and local taxi services available |
| Shuttle Service | Mayo Clinic offers a complimentary shuttle for patients and visitors |
| Public Transit | Rochester Public Transit (RPT) Route 3 (check schedule for availability) |
| Parking at Mayo Clinic | Multiple parking ramps available (fees apply) |
| Walking Distance | Not feasible due to distance |
| Airport to Mayo Clinic | Head northeast on Airport Dr, follow signs to Mayo Clinic |
| GPS Coordinates | Mayo Clinic: 44.0216° N, 92.4687° W |
| Estimated Cost (Taxi) | $20-$30 (one way) |
| **Estimated Cost (Rideshare) | $15-$25 (one way) |
| Shuttle Schedule | Check Mayo Clinic website for shuttle timings |
| Bus Fare (RPT) | $1.50 (one way) |
| Travel Tips | Plan for traffic during peak hours; book shuttle or rideshare in advance |
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What You'll Learn
- Transport Options: Taxi, rideshare, shuttle, or rental car availability from Rochester Airport to Mayo Clinic
- Public Transit: Bus routes and schedules connecting Rochester Airport to Mayo Clinic
- Driving Directions: Step-by-step driving instructions from the airport to Mayo Clinic
- Shuttle Services: Mayo Clinic’s shuttle availability, timings, and pickup locations from the airport
- Estimated Travel Time: Time taken by different modes of transport from Rochester Airport to Mayo Clinic

Transport Options: Taxi, rideshare, shuttle, or rental car availability from Rochester Airport to Mayo Clinic
Traveling from Rochester International Airport to Mayo Clinic offers several transport options, each catering to different needs and preferences. Taxis are readily available at the airport and provide a direct, hassle-free journey to the clinic. The trip typically takes 15–20 minutes, depending on traffic, and costs around $20–$25. This option is ideal for those seeking convenience and immediate departure without pre-booking.
For budget-conscious travelers, rideshare services like Uber and Lyft are popular alternatives. These platforms often cost less than traditional taxis, with fares starting at approximately $15. However, availability can vary, especially during peak hours or inclement weather. It’s advisable to check the app for real-time pricing and wait times before relying on this option. Ridesharing is best suited for individuals or small groups comfortable with app-based services.
Shuttle services offer a cost-effective and communal transport solution, particularly for those traveling alone or with minimal luggage. The Rochester Public Transit system operates buses that connect the airport to downtown Rochester, with stops near Mayo Clinic. A one-way fare is around $2, making it the most affordable option. However, this method requires adherence to bus schedules and may involve a short walk from the drop-off point to the clinic. Shuttles are ideal for patients or visitors prioritizing savings over speed.
Renting a car provides maximum flexibility, allowing travelers to explore Rochester beyond their Mayo Clinic visit. Major rental agencies like Hertz, Enterprise, and Avis have counters at the airport, with rates starting at $50 per day. This option is particularly useful for those with appointments spanning multiple days or requiring frequent trips between the clinic and accommodations. However, parking at Mayo Clinic can be costly, with daily rates ranging from $10–$20, so factor this into your budget. A rental car is best for those valuing independence and convenience.
Each transport option from Rochester Airport to Mayo Clinic has its merits, depending on your priorities. Taxis and rideshares excel in speed and simplicity, while shuttles offer affordability. Rental cars provide freedom but come with additional costs. Consider your schedule, budget, and personal preferences to choose the most suitable method for your journey.
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Public Transit: Bus routes and schedules connecting Rochester Airport to Mayo Clinic
Navigating public transit from Rochester International Airport (RST) to Mayo Clinic requires a clear understanding of the available bus routes and schedules. The Rochester Public Transit system, operated by the City of Rochester, offers a cost-effective and reliable option for travelers. Route 3 is the primary bus line connecting the airport to downtown Rochester, with several stops within walking distance of Mayo Clinic’s main campus. Buses run approximately every 30 minutes during peak hours (6:00 AM to 6:00 PM) and hourly during off-peak times, making it essential to plan your trip around these schedules. Fares are $1.00 per ride, with free transfers available within 90 minutes of boarding.
To begin your journey, locate the bus stop at the airport, situated near the baggage claim area. Route 3 buses are marked clearly, and drivers are typically helpful in assisting first-time riders. The trip to downtown Rochester takes approximately 20 minutes, depending on traffic. Once downtown, disembark at the 2nd Street SW & 3rd Avenue SW stop, which is a 10-minute walk from Mayo Clinic’s Gonda Building. Alternatively, transfer to Route 6 at the same stop for a direct connection to the clinic’s Saint Marys Campus, adding about 5 minutes to your travel time.
For those arriving outside of regular bus hours, consider using the Rochester Public Transit’s Night Owl service, which operates from 6:00 PM to 10:30 PM on weekdays. However, this service requires reservations made at least two hours in advance, so plan accordingly. Additionally, the transit system offers a mobile app, RideRTC, which provides real-time bus tracking and schedule updates, ensuring you stay informed about any delays or route changes.
A practical tip for travelers is to purchase a day pass for $2.50, which allows unlimited rides on all routes for 24 hours. This is particularly useful if you plan to explore Rochester beyond Mayo Clinic. Keep in mind that buses do not operate on major holidays, so check the schedule in advance if your travel coincides with these dates. By familiarizing yourself with these routes and schedules, you can efficiently navigate public transit from Rochester Airport to Mayo Clinic, saving both time and money.
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Driving Directions: Step-by-step driving instructions from the airport to Mayo Clinic
Navigating the 10-mile stretch from Rochester International Airport (RST) to Mayo Clinic’s Saint Marys Campus is straightforward, requiring approximately 15–20 minutes without traffic. Begin by exiting the airport terminal and turning left onto 60th Avenue NW. This initial step sets the course for a seamless journey, with clear signage guiding you toward Highway 52 North.
Once on 60th Avenue NW, drive for 0.3 miles before turning right onto U.S. Highway 52 North. This highway is your primary route, and staying on it for about 8 miles is crucial. Avoid the temptation to exit prematurely, as the road is well-marked and designed to funnel drivers directly toward downtown Rochester. Keep an eye on speed limits, which fluctuate between 60–65 mph, and be cautious of occasional construction zones that may slow traffic.
After approximately 8 miles on Highway 52 North, take Exit 56B for 2nd Street SW. This exit is a pivotal turn, leading you into the heart of Rochester. Turn left onto 2nd Street SW and proceed for 0.7 miles. The road will curve slightly, but continue straight, passing through two traffic lights. At the third light, turn right onto 3rd Avenue SW. This street is lined with medical facilities, signaling your proximity to Mayo Clinic.
Drive 0.4 miles on 3rd Avenue SW until you reach the entrance to Mayo Clinic’s Saint Marys Campus on your left. Parking options include the Ramp 4 visitor parking garage, accessible via a well-marked entrance. For drop-offs, use the designated area near the main entrance. If heading to the Mayo Clinic Downtown Campus instead, continue on 3rd Avenue SW for an additional 0.3 miles, turning left onto 2nd Street SW and following signs to your destination.
Practical tips: Use a GPS app for real-time traffic updates, especially during peak hours (7–9 AM and 4–6 PM). If traveling in winter, ensure your vehicle is equipped with snow tires or chains, as Minnesota’s weather can make roads slippery. Keep a small map or written directions as a backup, as cell service can occasionally be spotty along the route. With these steps and precautions, your drive from Rochester Airport to Mayo Clinic will be efficient and stress-free.
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Shuttle Services: Mayo Clinic’s shuttle availability, timings, and pickup locations from the airport
Mayo Clinic offers a complimentary shuttle service for patients and visitors traveling from Rochester International Airport (RST), ensuring a seamless transition to their medical appointments. This service is particularly beneficial for those unfamiliar with the area or seeking a hassle-free transportation option. The shuttle operates on a scheduled basis, with timings designed to accommodate most flight arrivals and departures. To utilize this service, passengers must first confirm their eligibility and reserve a seat, as availability can vary depending on demand and clinic schedules.
The shuttle pickup location at Rochester Airport is conveniently situated near the baggage claim area, making it easily accessible for arriving passengers. Clear signage and clinic representatives are typically present to guide travelers to the designated pickup point. It’s essential to arrive at the pickup location promptly, as the shuttle adheres to a strict schedule to ensure timely arrivals at Mayo Clinic. For those with mobility concerns, the shuttle is equipped to accommodate wheelchairs and other assistive devices, though advance notification is recommended to ensure appropriate arrangements.
Timings for the shuttle service are coordinated with flight schedules, but it’s advisable to verify the exact departure times upon arrival. The journey from the airport to Mayo Clinic takes approximately 15–20 minutes, depending on traffic conditions. Patients with early morning appointments should confirm the availability of the shuttle for their specific time slot, as the first pickup may not align with very early flights. Conversely, late-night arrivals may require alternative transportation arrangements, as the shuttle service typically concludes by early evening.
For practical tips, travelers should plan to book their shuttle reservation at least 48 hours in advance, especially during peak clinic hours or seasons. This ensures a guaranteed spot and minimizes wait times. Additionally, passengers should keep their confirmation details handy, as these may be required for boarding. While the shuttle is free of charge, gratuities for drivers are not expected but are appreciated for exceptional service. By leveraging Mayo Clinic’s shuttle service, patients and visitors can focus on their health needs without the added stress of navigating transportation logistics.
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Estimated Travel Time: Time taken by different modes of transport from Rochester Airport to Mayo Clinic
Traveling from Rochester International Airport to Mayo Clinic involves a short but crucial journey, with travel times varying significantly depending on your mode of transport. Understanding these differences can help you plan efficiently, especially if you’re visiting for medical appointments where punctuality is key. Here’s a breakdown of estimated travel times and practical considerations for each option.
By Car (Rental or Ride-Share): The most direct route spans approximately 8 miles, taking around 15–20 minutes under normal traffic conditions. Opt for Highway 63 North, which leads straight to Mayo Clinic’s main campus. Pro tip: Allow extra time during peak hours (7–9 AM and 4–6 PM) or if road construction is underway. Parking at Mayo Clinic can be tight, so consider valet services or pre-booking a spot via their online system to save time.
By Public Transit: Rochester’s bus system, operated by Rochester Public Transit (RPT), offers a budget-friendly option but requires careful planning. Route 3 connects the airport to downtown, with a transfer to Route 6 or 12 to reach Mayo Clinic. Total travel time averages 45–60 minutes, including wait times and transfers. Note: Buses run less frequently on weekends and evenings, so verify schedules on the RPT website beforehand.
By Taxi or Shuttle: Taxis and airport shuttles provide a middle ground between convenience and cost, with travel times mirroring private cars (15–20 minutes). Shuttle services like Groome Transportation offer fixed schedules and drop-off points near Mayo Clinic, while taxis can be hailed on-demand. For groups or families, splitting the fare makes this option more economical than ride-shares.
By Foot or Bike: While the airport is relatively close to Mayo Clinic, walking or biking isn’t practical due to the distance and lack of dedicated pathways. The 8-mile trek would take approximately 2.5–3 hours on foot or 45–60 minutes by bike, making it unsuitable for most travelers, especially those with medical appointments.
In summary, your choice of transport hinges on priorities: speed (car or taxi), cost (public transit), or convenience (shuttle). Plan ahead, factor in potential delays, and choose the mode that aligns best with your schedule and needs.
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Frequently asked questions
The closest airport to Mayo Clinic is the Rochester International Airport (RST), located approximately 8 miles from the clinic.
Transportation options include taxi services, ride-sharing apps (Uber/Lyft), shuttle services, and rental cars. Mayo Clinic also offers a complimentary shuttle for patients and visitors.
The drive typically takes 10–15 minutes, depending on traffic and weather conditions.
Yes, Mayo Clinic offers a complimentary shuttle service for patients and visitors. It operates on a scheduled basis and requires advance reservation.
Yes, several rental car companies operate at Rochester Airport, including Enterprise, Hertz, Avis, and Budget. Reservations can be made online or at the airport.











































